Major European stock indices closed mostly decline. DAX down 0.039%, FTSE 100 down 0.87%, CAC 40 rose by 0.21%. The fall is a correction after active growth in European sites on Monday, stimulated by positive news of coronavirus vaccine trials. Players expect that next year the majority of the population in different countries will be able to get the drug, the agency leads Reuters opinion of the head of strategy of investment in stocks Asia-Pacific Region of Herald Van Der Linde. Investors hope that with this the situation, the world economy will be able to recover soon. However, now the main factor affecting the quotes of the world exchanges, the second wave of the pandemic continues to appear - the number of diseases continues to grow, and quarantine restrictions in different countries - to tighten. American indices also closed lower after Tuesday's record high - decline amounted to 0.21 - 0.56%.